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Article

The diverse roles of autophagy in medically important fungi

16 Nov 2008

Abstract excerpt

Autophagy is a highly conserved eukaryotic mechanism whereby cells recycle cellular elements to survive under adverse conditions. Surprisingly, of the three fungal pathogens of greatest relevance to human health, only Cryptococcus neoformans has been shown to require this process during infection. In contrast, autophagy is dispensable for the virulence of both Candida albicans and Aspergillus fumigatus. The...

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PMID: 18927489
DOI: 10.4161/auto.7075

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