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The Autophagy Machinery in Human-Parasitic Protists; Diverse Functions for Universally Conserved Proteins

19 May 2021

Abstract excerpt

Autophagy is a eukaryotic cellular machinery that is able to degrade large intracellular components, including organelles, and plays a pivotal role in cellular homeostasis. Target materials are enclosed by a double membrane vesicle called autophagosome, whose formation is coordinated by autophagy-related proteins (ATGs). Studies of yeast and Metazoa have identified approximately 40 ATGs. Genome projects for...

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PMID: 34069694
DOI: 10.3390/cells10051258

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