Article
[Hereditary breast carcinomas pathologist's perspective].
Annales de pathologie - 1 Apr 2020
Vincent-Salomon Anne, Bataillon Guillaume, Djerroudi Lounes
Abstract excerpt
Breast cancers occurring in the context of a hereditary mutation of a predisposition gene represent 5 to 10% of all breast cancers, 20 to 25% of which being due to a mutation in the BRCA1 or BRCA2 genes. Authorization to market PARP inhibitors for breast cancer patients with hereditary BRCA1 and 2 mutations has recently been obtained. Given the annual frequency of breast cancer, morphological identification could...
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