Article
[Hereditary breast and ovarian cancers].
Der Pathologe - 1 Oct 2010
Gevensleben H, Serçe N, Büttner R
Abstract excerpt
Hereditary factors are responsible for 5-10% of all breast cancers and 10% of all ovarian cancer cases and are predominantly caused by mutations in the high risk genes BRCA1 and BRCA2 (BRCA: breast cancer). Additional moderate and low penetrance gene variants are currently being analyzed via whole genome association studies. Interdisciplinary counseling, quality managed genetic testing and intensified prevention...
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