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Article

CDH1 mutations in gastric cancers are not associated with family history.

Pathology, research and practice - 1 May 2020

Choi Sangjoon, Jang Jiryeon, Heo You Jeong, Kang So Young, Kim Seung Tae, Lee Jeeyun, Kang Won Ki, Kim Jong-Won, Kim Kyoung-Mee

Abstract excerpt

CDH1 mutation is the most frequent genetic alteration in hereditary diffuse gastric cancer (GC) and early onset diffuse GC patients. However, the incidence of CDH1 mutations in sporadic GC with or without family history has not been studied. This retrospective study includes a total of 993 Korean patients with primary advanced GC who underwent surgery and received palliative chemotherapy. Targeted deep sequencing...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Antigens, CD
Cadherins
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Retrospective Studies

Stomach Neoplasms

Young Adult

Source

Identifiers

PMID: 32241597
DOI: 10.1016/j.prp.2020.152941

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32241597-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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