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Article

Prognostic impact of distinct genetic entities in pediatric diffuse glioma WHO-grade II-Report from the German/Swiss SIOP-LGG 2004 cohort.

International journal of cancer - 15 Oct 2020

Falkenstein Fabian, Gessi Marco, Kandels Daniela, Ng Ho-Keung, Schmidt René, Warmuth-Metz Monika, Bison Brigitte, Krauss Juergen, Kortmann Rolf-Dieter, Timmermann Beate, Thomale Ulrich-Wilhelm, Albert Michael H, Pekrun Arnulf, Maaß Eberhard, Gnekow Astrid K, Pietsch Torsten

Abstract excerpt

Reports on pediatric low-grade diffuse glioma WHO-grade II (DG2) suggest an impaired survival rate, but lack conclusive results for genetically defined DG2-entities. We analyzed the natural history, treatment and prognosis of DG2 and investigated which genetically defined sub-entities proved unfavorable for survival. Within the prospectively registered, population-based German/Swiss SIOP-LGG 2004 cohort 100...

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PMID: 32239677
DOI: 10.1002/ijc.32995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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