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Article

Defining an embryonal rhabdomyosarcoma endotype.

Cold Spring Harbor molecular case studies - 1 Apr 2020

Ricker Cora A, Crawford Kenneth, Matlock Kevin, Lathara Melvin, Seguin Bernard, Rudzinski Erin R, Berlow Noah E, Keller Charles

Abstract excerpt

Rhabdomyosarcoma (RMS) is the most common childhood soft-tissue sarcoma. The largest subtype of RMS is embryonal rhabdomyosarcoma (ERMS) and accounts for 53% of all RMS. ERMS typically occurs in the head and neck region, bladder, or reproductive organs and portends a promising prognosis when localized; however, when metastatic the 5-yr overall survival rate is ∼43%. The genomic landscape of ERMS demonstrates a...

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Identifiers

PMID: 32238403
DOI: 10.1101/mcs.a005066
PMCID: PMC7133750

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