Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct patterns of mutational sensitivity for λ resistance and maltodextrin transport in Escherichia coli LamB.

Microbial genomics - 1 Apr 2020

Andrews Bryan, Fields Stanley

Abstract excerpt

Bacteria can evade cohabiting phages through mutations in phage receptors, but these mutations may come at a cost if they disrupt the receptor's native cellular function. To investigate the relationship between these two conflicting activities, we generated sequence-function maps of Escherichia coli LamB with respect to sensitivity to phage λ and transport of maltodextrin. By comparing 413 missense mutations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Outer Membrane Proteins
Share to Bacteriophage lambda
Share to Mutation, Missense

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polysaccharides

Share to Porins

Share to Protein Conformation

Share to Protein Stability

Share to Receptors, Virus

Source

Open in PubMed Open full text

Identifiers

PMID: 32238226
DOI: 10.1099/mgen.0.000364
PMCID: PMC7276705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct patterns of mutational sensitivity for λ resistance and maltodextrin transport in Escherichia coli LamB.PMID 32238226Read ↗

Destabilizing mutations encode nongenetic variation that drives evolutionary innovation.Semantic proximity Read ↗

Screening for lamB missense mutations which alter all lambda receptor activities in Escherichia coli K12.Semantic proximity Read ↗

Characterization of phage evolution and phage resistance in drug-resistant Stenotrophomonas maltophilia.Semantic proximity Read ↗

Mapping the functional landscape of the receptor binding domain of T7 bacteriophage by deep mutational scanning.Semantic proximity Read ↗

Sustained coevolution of phage Lambda and Escherichia coli involves inner- as well as outer-membrane defences and counter-defences.Semantic proximity Read ↗

Balance between promiscuity and specificity in phage λ host range.Semantic proximity Read ↗

Repeatability and contingency in the evolution of a key innovation in phage lambda.Semantic proximity Read ↗

Combinatorial mutagenesis of the lamB gene: residues 41 through 43, which are conserved in Escherichia coli outer membrane proteins, are informationally important in maltoporin structure and function.Semantic proximity Read ↗

Phage Resistance in Multidrug-Resistant Klebsiella pneumoniae ST258 Evolves via Diverse Mutations That Culminate in Impaired Adsorption.Semantic proximity Read ↗

Manipulating Interactions between T4 Phage Long Tail Fibers and Escherichia coli Receptors.Semantic proximity Read ↗

Bacteriophage lambda overcomes a perturbation in its host-viral genetic network through mutualism and evolution of life history traits.Semantic proximity Read ↗

Multisite binding of bacteriophages on lipopolysaccharides in Escherichia coli O157:H7 and the adaptive costs of phage resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.