Article
Apoptotic Markers Are Increased in Epilepsy Patients: A Relation with Manganese Superoxide Dismutase Ala16Val Polymorphism and Seizure Type through IL-1β and IL-6 Pathways.
BioMed research international - 1 Jan 2020
Kegler Aline, Caprara Ana Letícia Fornari, Pascotini Eduardo Tanuri, Arend Josi, Gabbi Patricia, Duarte Marta M M F, Furian Ana Flavia, Oliveira Mauro Schneider, Royes Luiz Fernando Freire, Fighera Michele Rechia
Abstract excerpt
The MnSOD Ala16Val single nucleotide polymorphism (SNP) has been associated with different diseases. However, there are scarcely studies relating this SNP in epilepsy, a neurologic disease that involves some interacting pathways, such as apoptotic and inflammatory factors. In this sense, we decided to investigate the relationship of MnSOD Ala16Val SNP with apoptotic markers in epilepsy and its relation with...
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