Article
Association of IL6 single nucleotide polymorphisms with febrile seizures.
Journal of the neurological sciences - 15 Jul 2014
Shahrokhi Amin, Zare-Shahabadi Ameneh, Soltani Samaneh, Ashrafi Mahmoud Reza, Zoghi Samaneh, Hosseini Seyed Ahmad, Heidari Moreteza, Yaghmaei Bahareh, Pourakbari Babak, Rezaei Nima
Abstract excerpt
Febrile seizures (FSs) are the most common convulsive event in children. Inflammatory elements and genetics have major roles in their pathogenesis. As of the importance of interleukin-6 (IL-6) in FS, this study was performed to assess IL6 single nucleotide polymorphisms (SNPs) in a group of patients with FS. IL6 gene (-174 and +565) SNPs were studied on genomic DNAs of 90 children with FS, using PCR-SSP method....
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