Article
Neuroinflammation in long COVID: the role of the Val16Ala polymorphism of SOD2 and cognitive impairment.
Neuroscience - 15 Oct 2025
do Nascimento Kimberly Fontoura, Alchieri Eduardo Felipe, Sanson Carolina Sanguinet, Andrade Cavalli Maria Eduarda, Moreira Pena Yuri Augusto, Okumura Tioda Ighor Senji, de Oliveira Laura Eduarda, Arend Josi, Duarte Marta M M F, Paniz Clóvis, Oliveira Mauro Schneider, Furian Ana Flavia, Freire Royes Luiz Fernando, Fighera Michele Rechia
Abstract excerpt
Long COVID (LC) includes persistent behavioral and cognitive deficits, impacting quality of life. Neuroinflammation plays a key role in these alterations, with genetic factors influencing susceptibility. The MnSOD Val16Ala SNP is associated with neuroinflammation and cognitive dysfunction, but its role in LC remains unclear. This study investigated the relationship between the SOD2 Val16Ala polymorphism and...
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