Article
Podoplanin discriminates distinct stromal cell populations and a novel progenitor subset in the liver.
American journal of physiology. Gastrointestinal and liver physiology - 1 Jan 2016
Eckert Christoph, Kim Yong Ook, Julich Henrike, Heier Eva-Carina, Klein Niklas, Krause Elmar, Tschernig Thomas, Kornek Miroslaw, Lammert Frank, Schuppan Detlef, Lukacs-Kornek Veronika
Abstract excerpt
Podoplanin/gp38(+) stromal cells present in lymphoid organs play a central role in the formation and reorganization of the extracellular matrix and in the functional regulation of immune responses. Gp38(+) cells are present during embryogenesis and in human livers of primary biliary cirrhosis. Since little is known about their function, we studied gp38(+) cells during chronic liver inflammation in models of...
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