Article
Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population.
Proceedings of the National Academy of Sciences of the United States of America - 4 Aug 2009
Nakano Masakazu, Ikeda Yoko, Taniguchi Takazumi, Yagi Tomohito, Fuwa Masahiro, Omi Natsue, Tokuda Yuichi, Tanaka Masami, Yoshii Kengo, Kageyama Masaaki, Naruse Shigeta, Matsuda Akira, Mori Kazuhiko, Kinoshita Shigeru, Tashiro Kei
Abstract excerpt
Primary open-angle glaucoma (POAG) is the major type of glaucoma. To discover genetic markers associated with POAG, we examined a total of 1,575 Japanese subjects in a genome-wide association study (stage 1) and a subsequent study (stage 2). Both studies were carried out at a single institution....
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