Article
The -174G>C and -596G>A Polymorphisms Are Not Associated with Circulating IL-6 Levels in Breast Cancer Patients from Jalisco, México.
Genetic testing and molecular biomarkers - 1 Apr 2020
Javalera David, Quintero-Ramos Antonio, Medina-Mora Yadira, Del Toro-Arreola Alicia, Franco-Topete Ramon Antonio, Oceguera-Villanueva Antonio, Barragán-Ruiz Adelfo, Flores-Márquez Maria Rosa, Topete Antonio, Daneri-Navarro Adrian
Abstract excerpt
Introduction: Interleukin-6 (IL-6) is a circulating proinflammatory cytokine that fulfills an important role in the survival and proliferation of cancer cells. Overexpression of IL-6, possibly due to the -174G>C and -596G>A polymorphisms in the IL6 gene, has been shown to be related to breast cancer (BC) and a more aggressive course of the disease. Aim: To determine the influence of the -174G>C and -596G>A...
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