Article
The Landscape and Prognosis Potential of the T-Cell Repertoire in Membranous Nephropathy.
Frontiers in immunology - 1 Jan 2020
Zhang Yu, Jin Yabin, Guan Zhanwen, Li Huishi, Su Zuhui, Xie Chao, Chen Xiangping, Liu Xiaofen, Pan Yingming, Ye Peiyi, Zhang Lifang, Kong Yaozhong, Luo Wei
Abstract excerpt
Membranous nephropathy (MN), a common pathological type of adult nephrotic syndrome, is an antibody-mediated kidney disease. It is widely accepted now that MN is an immune-related disease that involves the whole immune system. In this study, we analyzed the T-cell receptor beta chain (TCRβ) repertoire of the circulating T lymphocytes of MN patients and healthy controls using high-throughput sequencing. We...
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