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Article

Phenotypic Diversity Caused by Differential Expression of SFTPC-Cre-Transgenic Alleles.

American journal of respiratory cell and molecular biology - 1 Jun 2020

Jiang Mao, Roth Mark G, Chun-On Pattra, Sullivan Daniel I, Alder Jonathan K

Abstract excerpt

Type II alveolar epithelial cells (AEC2s) play an essential role in the function and maintenance of the pulmonary epithelium. Several transgenic mice have been developed to study the function of these cells in vivo by using the human SFTPC promoter to drive expression of Cre recombinase. The precise activity of each of these transgenic alleles has not been studied, and previous reports suggest that their activity...

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Identifiers

PMID: 32208105
DOI: 10.1165/rcmb.2019-0416MA
PMCID: PMC7258818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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