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Alzheimer-related genes show accelerated evolution

12 Mar 2020

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disorder of unknown cause with complex genetic and environmental traits. While AD is extremely prevalent in human elderly, it hardly occurs in non-primate mammals and even non-human-primates develop only an incomplete form of the disease. This specificity of AD to human clearly implies a phylogenetic aspect. Still, the evolutionary dimension of AD pathomechanism...

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PMID: 32203153
DOI: 10.1038/s41380-020-0680-1

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