Article
Dramatic changes in the electrochemical and spectroscopic behavior of DNA fragments induced by the loss of a single nucleotide.
Bioelectrochemistry (Amsterdam, Netherlands) - 1 Aug 2020
Triskova Iveta, Veznik Jakub, Lacina Karel, Trnkova Libuse
Abstract excerpt
In this paper, the d(GCGAAGC) heptamer and the closely related d(GCGAGC) hexamer are examined via electrochemical (cyclic voltammetry) and spectroscopic (circular dichroism) methods. Dramatic changes in the CD spectroscopic and CV electrochemical properties, induced by the loss of only one single nucleotide (A), are detected. The CD spectra and native polyacrylamide gel electrophoresis (PAGE) confirmed structural...
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