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Article

Molecular Profiling of the Metaplastic Spindle Cell Carcinoma of the Breast Reveals Potentially Targetable Biomarkers.

Clinical breast cancer - 1 Aug 2020

Vranic Semir, Stafford Phillip, Palazzo Juan, Skenderi Faruk, Swensen Jeffrey, Xiu Joanne, Spetzler David, Gatalica Zoran

Abstract excerpt

INTRODUCTION: Spindle cell carcinoma is a rare subtype of metaplastic breast cancer, with triple-negative (TNBC: estrogen receptor-negative/progesterone receptor-negative/human epidermal growth factor receptor 2-negative) phenotype. It is associated with a marked resistance to conventional chemotherapy and has an overall poor outcome. MATERIALS AND METHODS: Twenty-three pure spindle cell carcinomas of the breast...

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Identifiers

PMID: 32197944
DOI: 10.1016/j.clbc.2020.02.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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