Article
miRNA expression can classify pediatric thyroid lesions and increases the diagnostic yield of mutation testing.
Pediatric blood & cancer - 1 Jun 2020
Franco Aime T, Labourier Emmanuel, Ablordeppey Kenny Kwabena, Surrey Lea F, Mostoufi-Moab Sogol, Isaza Amber, Adzick N Scott, Kazahaya Ken, Kumar Gyanendra, Bauer Andrew J
Abstract excerpt
BACKGROUND: Genetic alterations in multiple cell signaling pathways are involved in the molecular pathogenesis of thyroid cancer. Oncogene mutation testing and gene-expression profiling are routinely used for the preoperative risk management of adult thyroid nodules. In this study, we evaluated the potential value of miRNA biomarkers for the classification of pediatric thyroid lesions. PROCEDURE: Double-blind...
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