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Article

Quantifying Differences in Heritability among Psoriatic Arthritis (PsA), Cutaneous Psoriasis (PsC) and Psoriasis vulgaris (PsV).

Scientific reports - 18 Mar 2020

Li Quan, Chandran Vinod, Tsoi Lam, O'Rielly Darren, Nair Rajan P, Gladman Dafna, Elder James T, Rahman Proton

Abstract excerpt

Chronic plaque psoriasis and psoriatic arthritis are multifactorial inter-related diseases with strong genetic contributions. Better elucidation of the heritability of psoriatic disease subsets is important for identifying novel genes, risk stratification and potential clinical applications. In this study, we used two mixed-effect modelling methodologies to assess the additive contribution of common single...

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Identifiers

PMID: 32188927
DOI: 10.1038/s41598-020-61981-5
PMCID: PMC7080781

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