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Article

Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach

17 Mar 2020

Abstract excerpt

BACKGROUND: Blood-retinal barrier cells are known to exhibit a massive phenotypic change during experimental autoimmune uveitis (EAU) development. In an attempt to investigate the mechanisms of blood-retinal barrier (BRB) breakdown at a global level, we studied the gene regulation of total retinal cells and retinal endothelial cells during non-infectious uveitis. METHODS: cells). EAU was induced in C57BL/6 mice...

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PMID: 32183784
DOI: 10.1186/s12886-020-1333-5

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