Article
CRB1-Associated Retinal Dystrophy Patients Have Expanded Lewis Glycoantigen-Positive T Cells.
Investigative ophthalmology & visual science - 3 Oct 2023
Moekotte Lude, Kuiper Jonas J W, Hiddingh Sanne, Nguyen Xuan-Thanh-An, Boon Camiel J F, van den Born L Ingeborgh, de Boer Joke H, van Genderen Maria M
Abstract excerpt
Purpose: Eye inflammation may occur in patients with inherited retinal dystrophies (IRDs) and is seen frequently in IRDs associated with mutations in the CRB1 gene. The purpose of this study was to determine the types of inflammatory cells involved in IRDs, by deep profiling the composition of peripheral blood mononuclear cells of patients with a CRB1-associated IRD. Methods: This study included 33 patients with...
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