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MERTK is a host factor that promotes classical swine fever virus entry and antagonizes innate immune response in PK-15 cells

1 Jan 2020

Abstract excerpt

family. To date, the host factors required for CSFV entry remain poorly characterized. To identify the functional membrane protein(s) involved in CSFV infection, we analyzed the transcriptomic data from previous studies describing gene expression profiles for CSFV, and found twelve novel candidate proteins. One of these proteins, MERTK, significantly reduced CSFV protein expression by RNA interference screening...

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PMID: 32172658
DOI: 10.1080/22221751.2020.1738278

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