Article
Structural Glycoprotein E2 of Classical Swine Fever Virus Critically Interacts with Host Protein Torsin-1A during the Virus Infectious Cycle.
Journal of virology - 24 May 2021
Vuono E A, Ramirez-Medina E, Velazquez-Salinas L, Berggren K, Rai A, Pruitt S, Espinoza N, Gladue D P, Borca M V
Abstract excerpt
The classical swine fever virus (CSFV) glycoprotein E2 is the major structural component of the virus particle. E2 is involved in several functions, such as virus adsorption to the cell, the elicitation of protective immune responses, and virus virulence in swine. Using a yeast two-hybrid system, we previously identified the swine host protein Torsin-1A, an ATPase protein residing in the endoplasmic reticulum and...
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