Article
[Cystic fibrosis--review].
Laeknabladid - 1 Dec 2008
Jonsdottir Brynja, Bergsteinsson Hordur, Baldursson Olafur
Abstract excerpt
The purpose of this paper is to give a brief overview of cystic fibrosis; its pathogenesis, diagnosis, treatment and prognosis. Cystic fibrosis is an autosomal recessive disorder, which is caused by a mutation in the CFTR protein, a chloride channel in epithelial cell membranes. More than 1500 mutations are known. The incidence is 1/2.000-3.000 in nations of European origin. The CFTR mutation influences the...
Topics
- Anti-Bacterial Agents
- Anti-Inflammatory Agents
- Bronchodilator Agents
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Disease Progression
- Expectorants
- Humans
- Mutation
- Time Factors
- Treatment Outcome
- United States