Article
Accurately estimating the length distributions of genomic micro-satellites by tumor purity deconvolution.
BMC bioinformatics - 11 Mar 2020
Wang Yixuan, Zhang Xuanping, Xiao Xiao, Zhang Fei-Ran, Yan Xinxing, Feng Xuan, Zhao Zhongmeng, Guan Yanfang, Wang Jiayin
Abstract excerpt
BACKGROUND: Genomic micro-satellites are the genomic regions that consist of short and repetitive DNA motifs. Estimating the length distribution and state of a micro-satellite region is an important computational step in cancer sequencing data pipelines, which is suggested to facilitate the downstream analysis and clinical decision supporting. Although several state-of-the-art approaches have been proposed to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.