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Article

PADI4 and the HLA-DRB1 shared epitope in juvenile idiopathic arthritis.

PloS one - 1 Jan 2017

Hisa Kaori, Yanagimachi Masakatsu D, Naruto Takuya, Miyamae Takako, Kikuchi Masako, Hara Rhoki, Imagawa Tomoyuki, Yokota Shumpei, Mori Masaaki

Abstract excerpt

OBJECTIVE: Both genetic and environmental factors are associated with susceptibility to juvenile idiopathic arthritis (JIA). Many studies have reported that both a 'shared epitope' (SE) encoded by several HLA-DRB1 alleles and the peptidyl arginine deiminase type 4 (PADI4) gene polymorphisms are associated with susceptibility to rheumatoid arthritis (RA). However, it is uncertain whether JIA and RA share the...

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Source

Open in PubMed Open full text

Identifiers

PMID: 28182665
DOI: 10.1371/journal.pone.0171961
PMCID: PMC5300194

Genes

PADI4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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PADI4 and the HLA-DRB1 shared epitope in juvenile idiopathic arthritis.PMID 28182665Read ↗

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