Article
Expression of Olig2, Nestin, NogoA and AQP4 have no impact on overall survival in IDH-wildtype glioblastoma.
PloS one - 1 Jan 2020
Behling Felix, Barrantes-Freer Alonso, Behnes Carl Ludwig, Stockhammer Florian, Rohde Veit, Adel-Horowski Antonia, Rodríguez-Villagra Odir Antonio, Barboza Miguel Angel, Brück Wolfgang, Lehmann Ulrich, Stadelmann Christine, Hartmann Christian
Abstract excerpt
Despite many years of research efforts and clinical trials the prognosis of patients diagnosed with glioblastoma remains very poor. The oligodendrocyte transcription factor 2 (Olig2) was identified as a marker for glioma stem cells, which are believed to be responsible for glioma recurrence and therapy resistance. In this retrospective analysis we assessed the prognostic value of oligodendroglial and glioma stem...
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