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A study of embryonic stem cell‐related proteins in human astrocytomas: Identification of Nanog as a predictor of survival

19 Aug 2013

Abstract excerpt

Recent studies suggest that the regulatory networks controlling the functions of stem cells during development may be abnormally active in human cancers. An embryonic stem cell (ESC) gene signature was found to correlate with a more undifferentiated phenotype of several human cancer types including gliomas, and associated with poor prognosis in breast cancer. In the present study, we used tissue microarrays of 80...

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PMID: 24037901
DOI: 10.1002/ijc.28441

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