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Cell‐surface‐bound circulating DNA in the blood: Biology and clinical application

15 May 2019

Abstract excerpt

Cell-surface-bound extracellular DNA (csbDNA) is present on the outer membrane of blood cells, including both red blood cells and leukocytes. Although less well characterized than cell-free DNA (cfDNA) in plasma and serum, leukocyte and red blood cell csbDNA form a considerable fraction of the blood extracellular nucleic acids pool, with typically at least comparable amount of DNA occurring bound to the outer...

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PMID: 31091350
DOI: 10.1002/iub.2070

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