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Article

Glycerol transport: an additional target for obesity therapy?

Trends in endocrinology and metabolism: TEM - 1 Apr 2006

Wintour E Marelyn, Henry Belinda A

Abstract excerpt

There is increasing evidence that the glycerol channel, aquaporin 7(AQP7), has an important role in adipose tissue formation and function--deletion of the gene in a mouse strain leads to obesity and diabetes type 2 if the mice are aged or fed earlier with a high-fat or sucrose diet. Can increased levels of AQP7 in adipose tissue protect against obesity? New studies on AQP7 highlight the important role of glycerol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16487720
DOI: 10.1016/j.tem.2006.01.009

Genes

AQP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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The metabolic implications of aquaporin 7 (AQP7) promoter variants in lean children and children with obesity.Semantic proximity Read ↗

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Knock-out models reveal new aquaporin functions.Semantic proximity Read ↗

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