Article
Is hormonal therapy after risk-reducing salpingo-oophorectomy associated with an increased risk of malignancy in pathogenic variant carriers?
Gynecologic oncology - 1 Jun 2020
Mills Kathryn A, Joshi Tanvi V, West Lindsay, Kuznicki Michelle, Kent Laura, Hokenstad Alexis N, Cripe James C, Woolfolk Candice, Senter Leigha, Bakkum-Gamez Jamie N, Wenham Robert M, Cohn David E, Bae-Jump Victoria, Thaker Premal H
Abstract excerpt
OBJECTIVES: This study aimed to assess the association between hormone replacement therapy and the incidence of subsequent malignancies in patients who underwent risk-reducing salpingo-oophorectomy and had mutations predisposing them to Müllerian cancers. METHODS: This Institutional Review Board-approved retrospective study was performed at five academic institutions. Women were included if they were age...
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