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[New Classification for Advanced Colorectal Cancer Using CancerPlex®Genomic Tests].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Nov 2016

Kameyama Hitoshi, Shimada Yoshifumi, Ichikawa Hiroshi, Nagahashi Masayuki, Sakata Jun, Kobayashi Takashi, Nogami Hitoshi, Maruyama Satoshi, Takii Yasumasa, Okuda Shujiro, Ling Yiwei, Izutsu Hiroshi, Kodama Keisuke, Nakada Mitsutaka, Wakai Toshifumi

Abstract excerpt

Recently, targeted drugs have been developed for the treatment of colorectal cancer(CRC). Among targets, it is well known that KRAS mutations are associated with resistance to epidermal growth factor receptor(EGFR)monoclonal antibodies. However, response rates using anti-EGFR monotherapy for CRC were less than 20-30% in previous clinical studies. Thus, because the RAS/MAP2K/MAPK and PI3K/AKT pathways are...

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PMID: 27899776

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EGFR
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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