Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low brain-derived neurotrophic factor protein levels and single-nucleotide polymorphism Val66Met are associated with peripheral neuropathy in type II diabetic patients.

Acta diabetologica - 1 Jul 2020

Azoulay David, Abed Sean, Sfadi Akram, Sheleg Ortal, Shaoul Ety, Shehadeh Mona, Kaykov Edward, Nodelman Marina, Bashkin Amir

Abstract excerpt

BACKGROUND: Studies by our group demonstrated brain-derived neurotrophic factor (BDNF) levels in blood and BDNF-Val66met-SNP as potential biomarkers in chemotherapy-induced peripheral neuropathy. Here, we evaluate symptoms of peripheral neuropathy (PN) and depression in patients with type II diabetes mellitus in search of an association with serum BDNF levels and the Val66Met-SNP. METHODS: In total, 90 patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Biomarkers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Diabetes Mellitus, Type 2

Share to Diabetic Neuropathies

Share to Methionine

Share to Peripheral Nervous System Diseases

Share to Valine

Source

Identifiers

PMID: 32124075
DOI: 10.1007/s00592-020-01508-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low brain-derived neurotrophic factor protein levels and single-nucleotide polymorphism Val66Met are associated with peripheral neuropathy in type II diabetic patients.PMID 32124075Read ↗

Dual mapping of MTHFR C677T (A1298C) and BDNF G196A (Val66Met) polymorphisms in patients with diabetic peripheral neuropathy.Semantic proximity Read ↗

Associations Between Previously Identified Genetic Variants and Clinical Phenotypes of Diabetic Neuropathy in Type 2 Diabetes: An Exploratory Analysis of the Discovery Cohort.Semantic proximity Read ↗

Prediction of Chemotherapy-Induced Peripheral Neuropathy in Patients with Lymphoma and Myeloma: the Roles of Brain-Derived Neurotropic Factor Protein Levels and A Gene PolymorphismSemantic proximity Read ↗

Sensory phenotype and risk factors for painful diabetic neuropathy: a cross-sectional observational study.Semantic proximity Read ↗

SCN9A Variants May be Implicated in Neuropathic Pain Associated With Diabetic Peripheral Neuropathy and Pain Severity.Semantic proximity Read ↗

Association between a MIR499A polymorphism and diabetic neuropathy in type 2 diabetes.Semantic proximity Read ↗

BDNF Val66Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.Semantic proximity Read ↗

Deciphering the molecular landscape of human peripheral nerves: implications for diabetic peripheral neuropathySemantic proximity Read ↗

Taxane-induced sensory peripheral neuropathy is associated with an SCN9A single nucleotide polymorphism in Japanese patients.Semantic proximity Read ↗

Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohortSemantic proximity Read ↗

The prevalence, distribution and impact of peripheral neuropathy among Danish patients with cancer – A population-based cross-sectional study.Semantic proximity Read ↗

Phenotypical characterization of exteroceptive sensation and pain symptoms on diabetic patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.