Article
SCN9A Variants May be Implicated in Neuropathic Pain Associated With Diabetic Peripheral Neuropathy and Pain Severity.
The Clinical journal of pain - 1 Nov 2015
Li Qingqin S, Cheng Peter, Favis Reyna, Wickenden Alan, Romano Gary, Wang Hao
Abstract excerpt
OBJECTIVES: Previous studies have established the role of SCN9A in various pain conditions, including idiopathic small fiber neuropathy. In the present study, we interrogate the relationship between common and rare variants in SCN9A gene and chronic neuropathic pain associated with diabetic peripheral neuropathy. DESIGN: Using a cohort of 938 patients of European ancestry with chronic neuropathic pain associated...
Topics
- Canada
- Chronic Pain
- Cohort Studies
- Diabetic Neuropathies
- Exons
- Female
- Genetic Predisposition to Disease
- Genetic Variation
- Genotyping Techniques
- Humans
- Introns
- Linkage Disequilibrium
- Male
- Middle Aged