Article
Exercise and arrhythmic risk in TMEM43 p.S358L arrhythmogenic right ventricular cardiomyopathy.
Heart rhythm - 1 Jul 2020
Paulin Frédéric L, Hodgkinson Kathleen A, MacLaughlan Sarah, Stuckless Susan N, Templeton Christina, Shah Suryakant, Bremner Heather, Roberts Jason D, Young Terry-Lynn, Parfrey Patrick S, Connors Sean P
Abstract excerpt
BACKGROUND: High-level exercise has been associated with a malignant phenotype in desmosomal and genotype-negative forms of arrhythmogenic right ventricular cardiomyopathy (ARVC). This is the first study to examine this issue with ARVC secondary to the TMEM43 p.S358L mutation. OBJECTIVE: The purpose of this study was to evaluate the impact of exercise on arrhythmic risk and cardiac death in TMEM43 p.S358L ARVC....
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