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Article

Exercise has a disproportionate role in the pathogenesis of arrhythmogenic right ventricular dysplasia/cardiomyopathy in patients without desmosomal mutations.

Journal of the American Heart Association - 1 Dec 2014

Sawant Abhishek C, Bhonsale Aditya, te Riele Anneline S J M, Tichnell Crystal, Murray Brittney, Russell Stuart D, Tandri Harikrishna, Tedford Ryan J, Judge Daniel P, Calkins Hugh, James Cynthia A

Abstract excerpt

BACKGROUND: Exercise is associated with age‐related penetrance and arrhythmic risk in carriers of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C)‐associated desmosomal mutations; however, its role in patients without desmosomal mutations (gene‐elusive) is uncertain. This study investigates whether exercise is (1) associated with onset of gene‐elusive ARVD/C and (2) has a differential impact in...

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Identifiers

PMID: 25516436
DOI: 10.1161/JAHA.114.001471
PMCID: PMC4338738

Genes

MET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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