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Article

Exercise increases age-related penetrance and arrhythmic risk in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated desmosomal mutation carriers.

Journal of the American College of Cardiology - 1 Oct 2013

James Cynthia A, Bhonsale Aditya, Tichnell Crystal, Murray Brittney, Russell Stuart D, Tandri Harikrishna, Tedford Ryan J, Judge Daniel P, Calkins Hugh

Abstract excerpt

OBJECTIVES: This study sought to determine how exercise influences penetrance of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) among patients with desmosomal mutations. BACKGROUND: Although animal models and anecdotal evidence suggest that exercise is a risk factor for ARVD/C, there have been no systematic human studies. METHODS: Eighty-seven carriers (46 male; mean age, 44 ± 18 years) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23871885
DOI: 10.1016/j.jacc.2013.06.033
PMCID: PMC3809992

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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