Article
Overall tumor genomic instability: an important predictor of recurrence-free survival in patients with localized clear cell renal cell carcinoma.
Cancer biology & therapy - 3 May 2020
Correa Andres F, Ruth Karen J, Al-Saleem Tahseen, Pei Jianming, Dulaimi Essel, Kister Debra, Collins Michelle, Abbosh Phillip H, Slifker Michael J, Ross Eric, Uzzo Robert G, Testa Joseph R
Abstract excerpt
Measurement of a tumor's overall genomic instability has gathered recent interest over the identification of specific genomic imbalances, as it may provide a more robust measure of tumor aggressiveness. Here we demonstrate the association of tumor genomic instability in the prediction of disease recurrence in patients with clinically localized clear cell renal cell carcinoma (ccRCC). Genomic copy number analysis...
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