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Article

Differential Frequency of CYP2R1 Variants Across Populations Reveals Pathway Selection for Vitamin D Homeostasis.

The Journal of clinical endocrinology and metabolism - 1 May 2020

Casella Alex, Long Caela, Zhou Jingman, Lai Meizan, O'Lear Lauren, Caplan Ilana, Levine Michael A, Roizen Jeffrey D

Abstract excerpt

CONTEXT: Normal vitamin D homeostasis is necessary to ensure optimal mineral metabolism. Dietary insufficiency of vitamin D and the lack of sunlight each have well understood roles in vitamin D deficiency; however, the extent to which common genetic variations in vitamin D metabolizing enzymes contribute to alterations in vitamin D homeostasis remains uncertain. OBJECTIVE: To examine the possibility that common...

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Identifiers

PMID: 32115644
DOI: 10.1210/clinem/dgaa056
PMCID: PMC7096315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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