Article
Avoiding New Biopsies by Identification of IDH1 and TERT Promoter Mutation in Nondiagnostic Biopsies From Glioma Patients.
Neurosurgery - 15 Sept 2020
Barritault Marc, Picart Thiébaud, Poncet Delphine, Fenouil Tanguy, d'Hombres Anne, Gabut Mathieu, Guyotat Jacques, Jouanneau Emmanuel, Ameli Roxana, Joubert Bastien, Streichenberger Nathalie, Vasiljevic Alexandre, Honnorat Jérôme, Meyronet David, Ducray François
Abstract excerpt
BACKGROUND: Biopsies in patients with a suspected glioma are occasionally nondiagnostic. OBJECTIVE: To explore the utility of molecular testing in this setting by determining whether IDH1 and TERT promoter (pTERT) mutations could be detected in nondiagnostic biopsies from glioma patients. METHODS: Using SNaPshot polymerase chain reaction, we retrospectively assessed IDH1 and pTERT mutation status in nondiagnostic...
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