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Article

Human Adventitial Fibroblast Phenotype Depends on the Progression of Changes in Substrate Stiffness.

Advanced healthcare materials - 1 Apr 2020

Scott Rebecca A, Robinson Karyn G, Kiick Kristi L, Akins Robert E

Abstract excerpt

Adventitial fibroblasts (AFs) are major contributors to vascular remodeling and maladaptive cascades associated with arterial disease, where AFs both contribute to and respond to alterations in their surrounding matrix. The relationships between matrix modulus and human aortic AF (AoAF) function are investigated using poly(ethylene glycol)-based hydrogels designed with matrix metalloproteinase (MMP)-sensitive and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32105417
DOI: 10.1002/adhm.201901593
PMCID: PMC7274877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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