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Article

Functional omics analyses reveal only minor effects of microRNAs on human somatic stem cell differentiation.

Scientific reports - 24 Feb 2020

Schira-Heinen Jessica, Czapla Agathe, Hendricks Marion, Kloetgen Andreas, Wruck Wasco, Adjaye James, Kögler Gesine, Werner Müller Hans, Stühler Kai, Trompeter Hans-Ingo

Abstract excerpt

The contribution of microRNA-mediated posttranscriptional regulation on the final proteome in differentiating cells remains elusive. Here, we evaluated the impact of microRNAs (miRNAs) on the proteome of human umbilical cord blood-derived unrestricted somatic stem cells (USSC) during retinoic acid (RA) differentiation by a systemic approach using next generation sequencing analysing mRNA and miRNA expression and...

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Identifiers

PMID: 32094412
DOI: 10.1038/s41598-020-60065-8
PMCID: PMC7040006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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