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Article

Discovering weaker genetic associations guided by known associations.

BMC medical genomics - 24 Feb 2020

Wang Haohan, Vanyukov Michael M, Xing Eric P, Wu Wei

Abstract excerpt

BACKGROUND: The current understanding of the genetic basis of complex human diseases is that they are caused and affected by many common and rare genetic variants. A considerable number of the disease-associated variants have been identified by Genome Wide Association Studies, however, they can explain only a small proportion of heritability. One of the possible reasons for the missing heritability is that many...

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Identifiers

PMID: 32093702
DOI: 10.1186/s12920-020-0667-4
PMCID: PMC7038505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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