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Article

Causal associations of waist circumference and waist-to-hip ratio with type II diabetes mellitus: new evidence from Mendelian randomization.

Molecular genetics and genomics : MGG - 1 May 2021

Li Kexin, Feng Tianyu, Wang Lijuan, Chen Yang, Zheng Pingping, Pan Pan, Wang Min, Binnay Isaac T S, Wang Yingshuang, Chai Ruiyu, Liu Siyu, Li Bo, Yao Yan

Abstract excerpt

Type II diabetes mellitus (T2DM) is a metabolic disease with high incidence, which has seriously affected human life and health. The associations among waist circumference (WC), waist-to-hip ratio (WHR), and T2DM were discovered in observational studies. However, the causality of these associations still remains unknown. The present study aims to apply two-sample Mendelian randomization (TSMR) using genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33629185
DOI: 10.1007/s00438-020-01752-z

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