Article
The extracytoplasmic function sigma factor σVreI is active during infection and contributes to phosphate starvation-induced virulence of Pseudomonas aeruginosa.
Scientific reports - 21 Feb 2020
Otero-Asman Joaquín R, Quesada José M, Jim Kin K, Ocampo-Sosa Alain, Civantos Cristina, Bitter Wilbert, Llamas María A
Abstract excerpt
The extracytoplasmic function sigma factor σVreI of the human pathogen Pseudomonas aeruginosa promotes transcription of potential virulence determinants, including secretion systems and secreted proteins. Its activity is modulated by the VreR anti-σ factor that inhibits the binding of σVreI to the RNA polymerase in the absence of a (still unknown) inducing signal. The vreI-vreR genes are expressed under inorganic...
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