Article
Hepcidin-mediated Iron Regulation in P19 Cells is Detectable by Magnetic Resonance Imaging.
Scientific reports - 21 Feb 2020
Alizadeh Kobra, Sun Qin, McGuire Tabitha, Thompson Terry, Prato Frank S, Koropatnick Jim, Gelman Neil, Goldhawk Donna E
Abstract excerpt
Magnetic resonance imaging can be used to track cellular activities in the body using iron-based contrast agents. However, multiple intrinsic cellular iron handling mechanisms may also influence the detection of magnetic resonance (MR) contrast: a need to differentiate among those mechanisms exists. In hepcidin-mediated inflammation, for example, downregulation of iron export in monocytes and macrophages involves...
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