Article
Single-nucleotide Polymorphism rs17860041 A/C in the Promoter of the PPIA Gene is Associated with Susceptibility to Kawasaki Disease in Chinese Children.
Immunological investigations - 1 Feb 2021
Shi Ruting, Luo Yeping, Li Shentang, Kong Min, Liu Xin, Yu Meng, Wu Jiping, Huang Lihua, Yang Zuocheng
Abstract excerpt
Background: Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology. Cyclophilin A (CypA), also known as PPIA, has been identified to play a vital role in the pathogenesis of cardiovascular or inflammatory diseases. However, no studies have examined the relationship between single-nucleotide polymorphisms (SNPs) in the peptidylprolyl isomerase A (PPIA) and the development of KD and KD with or...
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