Article
A Rapid Robust Method for Subgrouping Non-NF2 Meningiomas According to Genotype and Detection of Lower Levels of M2 Macrophages in AKT1 E17K Mutated Tumours.
International journal of molecular sciences - 13 Feb 2020
Adams Claire L, Ercolano Emanuela, Ferluga Sara, Sofela Agbolahan, Dave Foram, Negroni Caterina, Kurian Kathreena M, Hilton David A, Hanemann C Oliver
Abstract excerpt
The majority of meningiomas are grade I, but some grade I tumours are clinically more aggressive. Recent advances in the genetic study of meningiomas has allowed investigation into the influence of genetics on the tumour microenvironment, which is important for tumorigenesis. We have established that the endpoint genotyping method Kompetitive Allele Specific PCR (KASP™) is a fast, reliable method for the...
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